Every time I left for work, my dog Jinx would pace, pee on the hallway floor outside my room, chew the arm of the sofa, compulsively jump up on the kitchen counters with her front paws, and other stuff. She was wrecking my house and making it very hard for me to do anything or go anywhere. I tried pheromones and that did not work, then I tried a training DVD with no success. Clomipramine definitely helps. I am now using it along with some techniques a former pet trainer has given me. Fingers crossed.