One Shot Ultra 8 - 50 ds Vial contains inactivated whole cultures of P. haemolytica, as well as killed cultrues of Cl. chauvoei, Cl. septicum, Cl. haemolyticum, Cl. sordellii, Cl. Novyi, and Cl. perfringens types C and D. One Shot Ultra 8 also contains a unique, water-soluble adjuvant, Stimugen, which improves the immune response. Please Note: This product requires overnight expedited shipping and ships Monday through Thursday. During summer months, the purchase of 1 or 2 additional ice packs is advised.