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Neomycin, Polymyxin B, Bacitracin Opthalmic Ointment. with Hydrocortisone , 1/8 oz
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Item# 1010672
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    A broad spectrum antibiotic treatment along with an anti-inflammatory for external eye infections.


    Neomycin and Polymyxin B Sulfates, Bacitracin Zinc, and Hydrocortisone Ophthalmic Ointment, USP is a sterile anitmicrobial and anti-inflammatory ointment for ophthalmic use.

    Indications and Usage
    Neomycin and Polymyxin B sulfates, bacitracin zinc, and hydrocortisone ophthalmic ointment is indicated for steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where bacterial infection or a risk of bacterial infection exists.
    Ocular corticosteroids are indicated in inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the globe where the inherent risk of corticosteroid use in certain infective conjunctivitides is accepted to obtain a diminution in edema and inflammation. They are also indicated in chronic anterior uveitis and corneal injury from chemical, radiation, or thermal burns, or penetration of foreign bodies.
    The use of a combination drug with an anti-infective component is indicated where the risk of infection is high or where there is an expectation that potentially dangerous numbers of bacteria will be present in the eye.
    The particular anti-infective drugs in this product are active against the following common bacterial eye pathogens: Staphylococcus aureus, streptococci, including Streptococcus pneumonia, Escherichia coli, Haemophilus influenzae, Klebsiella-Enterobacter species, Neisseria species, and Pseudomonas aeruginosa. The product does not provide adequate coverage against Serratia marcescens.

    Neomycin and Polymyxin B sulfates, Bacitracin, and hydrocortisone ophthalmic ointment is contraindicated in most viral diseases of the cornea an conjunctiva including: epithelial herpes simplex keratitis, vaccinia and varicella, and also in mycobacterial infection of the eye and fungal diseases of ocular structures.
    This product is also contraindicated in individuals who have shown hypersensitivity to any of its components. Hypersensitivity to the antibiotic component occurs at a higher rate than for other components.

    Carcinogenesis, Mutagenensis, Impairment of Fertility
    Long-term studies in animals to evaluate carcinogenic or mutagenic potential have not been conducted with Polymyxin B sulfate or bacitracin. Treatment of cultured human lymphocytes in vitro with neomycin increased the frequency of chromosome aberrations at the highest concentration tested; however, the effects of neomycin on carcinogenesis and mutagenesis in humans are unknown.
    Long-term studies in animals showed no evidence of carcinogenicity or mutagenicity attributable to oral administration of corticosteroids. Long-term animal studies have not been performed to evaluate the carcinogenic potential of topical corticosteroids. Studies to determine mutagenicty with hydrocortisone have revealed negative results.
    Polymyxin B has been reported to impair the motility of equine sperm, but its effects on male or female fertility are unknown. No adverse effects on male or female fertility, litter size or survival were observed in rabbits given bacitracin zinc 100gm/ton of diet. Long-term animal studies have not been performed to evaluate the effect on fertility of topical corticosteroids.

    Pregnancy; Teratogenic Effects
    Pregnancy Category C. Corticosteroids have been found to be teratogenic in rabbits when applied topically at concentrations of 0.5% on days 6 to 18 of gestation and in mice when applied topically at a concentration of 15% on days 10 to 13 of gestation. There are no adequate and well-controlled studies in pregnant women. Neomycin and Polymyxin B sulfates, bacitracin zinc, and hydrocortisone ophthalmic ointment should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

    Nursing Mothers
    It is known whether topical administration of corticosteroids could result in sufficient systemic absorption to produce detectable quantities in human milk. Systemically administered corticosteroids appear in human milk and could suppress growth, interfere with endogenous corticosteroid production, or cause other untoward effects. Because of the potential for serious adverse reactions in nursing infants from neomycin and Polymyxin B sulfates, bacitracin zinc, and hydrocortisone ophthalmic ointment, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.

    Pediatric Use
    Safety and effectiveness in pediatric patients have not been established.

    Adverse Reactions
    Adverse reactions have occurred with corticosteroid/anti-infective combination drugs which can be attributed to the corticosteroid component, the anti-infective component, or the combination. The exact incidence is not known.
    Reactions occurring most often from the presence of the anti-infective ingredient are allergic sensitization reactions including itching, swelling and conjunctival erythema. More serious hypersensitivity reactions, including anaphylaxis, have been reported rarely.
    The reactions due to the corticosteroid component in decreasing order of frequency are: elevation of intraocular pressure with possible development of glaucoma, and infrequent optic nerve damage; posterior sub capsular cataract formation; and delayed wound healing.

    Secondary Infection
    The development of secondary infection has occurred after use of combinations containing corticosteroids and anitmicrobial. Fungal and viral infections of the cornea are particularly prone to develop coincidentally with long-term applications of a corticosteroid. The possibility of fungal invasion must be considered in any persistent corneal ulceration where corticosteroid treatment has been used.
    Local irritation on instillation has also been reported.

    Dosage and Administration
    Apply the ointment in the affected eye every 3 to 4 hours, depending on the severity of the condition.
    Not more than 8 grams should be prescribed initially and the prescription should not be refilled without further evaluation.


    Overall Customer Rating of 5 Reviews:

    eye med

    Love this med especially 4 elderly dogs & those with mucousy eyes. 1 or 2 applications of this product & problem disappears! Since I am involved in scottish terrier rescue, the reduced cost compared 2 vet office is great!

    Works very well

    • fast%20working
    My Collie had been scratching at her eye. It looked horrible and she had hair loss around her eye, scratches that wouldn't heal and the skin was flaky and dry. I started using this ointment twice a day and within days I saw improvement. Now, her hair has grown back and it looks great.

    east TN

    Neo-Poly-Bac-Hydro Ophthalmic Ointment

    My vet recommended this ointment for my Aussie. It lubricates the eye as well as treating it. I have used Butler products before and am very happy to have found this here at Vet Depot. I was very pleased with the service rendered by Vet Depot as well. I feel Butler produces good quality products at reasonable prices.

    Trenton, NJ

    Eye Ointment

    • Excellent product.
    Neo-Poly-Bac-Hydro worked right away to help the pain and redness in my dog's eye from infection.

    Neo-Poly-Bac-Hydro Ophthalmic Ointment, 1/8 oz

    My kitten had an eye infection that clouded her eye and made it hard for her to see. I went to our local vet & he gave me this--worked like a charm! Within 2 days she was back to her usual self.

    This information is for general reference only and should not be used for the diagnosis or treatment of any condition of your pet. Because is intended as a general reference, this information may not include all possible uses, precautions, directions, reactions (including allergic), drug interactions, or withdrawal times. Always consult your local veterinarian and have your pet examined for any advice concerning the diagnosis and treatment of your pet, including which products and doses are most appropriate. Any trademarks are the property of their respective owners. VetDepot is not a pharmacy. All prescription products are dispensed by our Pharmacy Partner.

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