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Frontline Plus for Cats, Green, 3 Pack
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Retail: $63.99
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Merial Item #: 1010192 -
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Topical flea and tick control for cats Use Frontline Plus for Cats, 3 Month (Green) to protect your pet from fleas and ticks for 30 days with just a single application. Frontline Plus combines Fipronil and (S)-methoprene to kill adult fleas, flea eggs and larvae, and ticks. The fact that it kills adult and immature fleas is what allows this product to break the flea life cycle and prevent future infestations. Because Frontline Plus for Cats is waterproof, your pet won't lose any pest...

Frontline Plus for Cats, Green, 6 Pack
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Merial Item #: 1010193 -
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Ends flea and tick infestations on cats Order Frontline Plus for Cats, 6 Month (Green) to keep your pet free from fleas, ticks, and chewing lice. This topical application is easy-to-use and offers 30 days of protection, even after swimming or bathing. Frontline Plus kills existing adult fleas within 12 hours of application and ticks within 48 hours, even those that may be carrying Lyme Disease. Some topical flea products only kill adult fleas, which means larvae can still mature and eggs can...

Frontline Plus for Cats, Green, 12 Pack
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Merial Item #: 1013918 -
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Flea and tick control for cats Frontline Plus for Cats, 12 Month (Green) is a topical flea and tick control product that offers up to 30 days of protection. This product contains two ingredients, Fipronil and (S)-methoprene, to kill adult fleas and ticks and flea eggs and larvae. This allows Frontline Plus to eliminate existing adult fleas within 12 hours and kill immature fleas to prevent reinfestations. Frontline Plus for Cats is safe for cats and kittens that are 8 weeks of age or older....

Frontline Plus for Dogs 0-22 lbs, Orange, 3 Pack
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Merial Item #: 1010177 -
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Proven flea and tick protection for dogs Frontline Plus for Dogs 0-22 lbs, 3 Month (Orange) is a topical flea and tick control product that offers up to 30 days of protection. This product contains two ingredients, Fipronil and (S)-methoprene, to kill adult fleas and ticks and flea eggs and larvae. This allows Frontline Plus to eliminate existing adult fleas within 12 hours and kill immature fleas to prevent reinfestations. Frontline Plus is also effective against American dog ticks, deer...


Frontline Plus for Dogs 0-22 lbs, Orange, 6 Pack
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Merial Item #: 1010178 -
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Monthly, topical flea and tick preventative for dogs Buy Frontline Plus for Dogs 0-22 lbs, 6 Month (Orange) from VetDepot today and use it to keep your small dog protected from fleas, ticks, and chewing lice. This product is a topical flea and tick preventative that you only have to apply once a month. It's easy to use and comes in pre-packaged applicators. Frontline Plus uses Fipronil to kill adult fleas on your pet within 12 hours of application and ticks within 48 hours. It also has the...

Frontline Plus for Dogs 0-22 lbs, Orange, 12 Pack
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Merial Item #: 1013919 -
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Apply Frontline Plus monthly for flea and tick protection Choose Frontline Plus for Dogs 0-22 lbs, 12 Month (Orange) to keep your small dog safe from fleas, ticks, and chewing lice year-round. The Fipronil and (S)-methoprene in Frontline Plus work together to kill all stages of fleas. This product also kills deer ticks, American dog ticks, brown dog ticks, and lone star ticks which can help keep your dog safe from Lyme Disease by preventing tick bites. Frontline Plus for Dogs is easy to use....

Frontline Plus for Dogs 23-44 lbs, Blue, 3 Pack
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Merial Item #: 1010187 -
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Ends flea and tick infestations on dogs Order Frontline Plus for Dogs 23-44 lbs, 3 Month (Blue) to keep your pet free from fleas, ticks, and chewing lice. You simply use one applicator per month on your pet's skin, and Frontline Plus handles the rest. It kills existing adult fleas within 12 hours of application and ticks within 48 hours, even those that may be carrying Lyme Disease. Some topical flea products only kill adult fleas, which means larvae can still mature and eggs can still hatch...

Frontline Plus for Dogs 23-44 lbs, Blue, 6 Pack
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Merial Item #: 1010188 -
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Monthly, topical flea and tick preventative for dogs Buy Frontline Plus for Dogs 23-44 lbs, 6 Month (Blue) today and use it to keep your medium dog protected from fleas, ticks, and chewing lice. This product is a topical flea and tick preventative that comes in easy-to-use, pre-packaged applicators. You only have to apply Frontline Plus once a month to give your pet effective protection against these pests. Frontline Plus uses Fipronil to kill adult fleas on your pet within 12 hours of...


Frontline Plus for Dogs 23-44 lbs, Blue, 12 Pack
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Merial Item #: 1013920 -
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Protect your dog from fleas and ticks with Frontline Plus Use Frontline Plus for Dogs 23-44 lbs, 12 Month (Blue) to protect your pet from fleas and ticks for 30 days with just a single application. Frontline Plus combines Fipronil and (S)-methoprene to kill adult fleas, flea eggs and larvae, and ticks. The fact that it kills the eggs and larvae is what allows it to break the flea life cycle and prevent future infestations. Because Frontline Plus for Dogs is waterproof, your pet won't lose any...

Frontline Plus for Dogs 45-88 lbs, Purple, 3 Pack
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Merial Item #: 1010189 -
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Flea and tick control for large dogs and puppies Frontline Plus for Dogs, 3 Month (Purple) is an over-the-counter flea and tick preventative that offers up to 30 days of protection. This product contains two ingredients, Fipronil and (S)-methoprene, to kill adult fleas and ticks, flea eggs, and flea larvae. This allows Frontline Plus to eliminate existing adult fleas within 12 hours and adult ticks within 48 hours. Frontline Plus for Dogs is safe for dogs and puppies that are 8 weeks of age or...

Frontline Plus for Dogs 45-88 lbs, Purple, 6 Pack
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Merial Item #: 1010190 -
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Order Frontline Plus for Dogs 45-88 lbs. today Frontline Plus for Dogs 45-88 lbs, 6 Month (Purple) contains two powerful ingredients that keep your dog free of parasites. The first one is Fipronil, which kills adult fleas already on your pet within 12 hours of application. The second ingredient, (S)-methoprene, kills flea eggs and larvae. Together they protect your pet for 30 days with just a single application. Because Frontline Plus kills immature fleas instead of just adults, it breaks the...

Frontline Plus for Dogs 45-88 lbs, Purple, 12 Pack
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Merial Item #: 1013921 -
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Use Frontline Plus to prevent flea and tick infestations Fleas and ticks are more than just a nuisance for your dog; they can cause flea bite allergies or even transmit serious illnesses like Lyme Disease or Rocky Mountain Spotted Fever. That's why it's so important to use a flea and tick preventative like Frontline Plus for Dogs 45-88 lbs, 12 Month (Purple). Frontline Plus stops flea infestations with its combination of Fipronil and (S)-methoprene. Fipronil kills adult fleas within 12 hours...


Frontline Plus for Dogs 89-132 lbs, Red, 3 Pack
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Merial Item #: 1010194 -
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Proven protection against fleas, ticks, and chewing lice Order Frontline Plus for Dogs 89-132 lbs, 3 Month (Red) to eliminate and prevent flea, tick, and chewing lice infestations. You simply apply one dose per month on your pet's skin, and Frontline Plus handles the rest. It kills existing adult fleas within 12 hours of application and multiple species of ticks within 48 hours, even those that may be carrying Lyme Disease. Some topical flea products only kill adult fleas, which means larvae...

Frontline Plus for Dogs 89-132 lbs, Red, 6 Pack
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Merial Item #: 1010191 -
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Monthly, topical flea and tick preventative for dogs Buy Frontline Plus for Dogs 89-132 lbs, 6 Month (Red) from VetDepot.com and use it to keep your extra-large dog protected from fleas, ticks, and chewing lice. This is a topical product that you only have to apply once a month. It's easy to use and comes in pre-packaged applicators. Frontline Plus uses Fipronil to kill adult fleas on your pet within 12 hours of application and ticks within 48 hours. It also uses the insect growth regulator...

Frontline Plus for Dogs 89-132 lbs, Red, 12 Pack
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Retail: $263.99
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Merial Item #: 1013922 -
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Kills fleas, flea eggs and larvae, and ticks Frontline Plus for Dogs 89-132 lbs, 12 Month (Red) is a topical flea and tick preventative that you apply monthly. The Fipronil in Frontline Plus allows it to kill 100% of existing adult fleas on your pet within 12 hours and 100% of ticks and chewing lice within 48 hours. The second ingredient, (S)-methoprene, functions as an insect growth regulator to kill flea eggs and larvae. This product is effective against all stages of American dog ticks,...


Frontline Plus Flea & Tick Control

Rating: based on 147 reviews

What is Frontline Plus?

Frontline Plus is a topical flea and tick preventative for dogs and cats that you apply monthly. It goes to work as soon as you apply it to your pet, killing 100% of adult fleas on your cat or dog within 12 hours and 100% of all ticks and chewing lice within 48 hours. But Frontline Plus doesn't kill only adult fleas. It also has an insect growth regulator (IGR) that eliminates flea eggs and larvae. Doing this keeps immature fleas from developing and effectively ends the infestation.

Frontline Plus lasts for up to four weeks even after swimming or bathing and is safe for use on dogs, cats, puppies, and kittens that are 8 weeks or older. Use it to keep your pet safe from fleas and all stages of American dog ticks, brown dog ticks, lone star ticks, and deer ticks (one of the major carries of Lyme Disease). Order Frontline Plus today to get fast convenient flea and tick control.

Benefits

  • Once-monthly application to kill fleas, ticks, and chewing lice
  • Prevents development of all stages of fleas, including eggs, larvae, pupae
  • Effective on deer ticks, American dog ticks, brown dog ticks, and lone star ticks
  • Quickly stops chewing lice infestations
  • Prevents and eliminates flea infestations and reinfestations
  • Helps control infestations of sarcoptic mange
  • Helps prevent allergic dermatitis caused by fleas and Lyme Disease resulting from tick bites
  • Safe for use during breeding or on pregnant and lactating bitches
  • Waterproof

How it Works

Frontline Plus for Dogs & Cats has two main ingredients that allow it to protect your pets from external parasites. First, Fipronil kills adult fleas and ticks by affecting their nervous systems. It gathers in the oils of your pet's skin and hair follicles and is slowly released for up to one month onto the skin and hair. Second, (S)-methoprene kills flea eggs and larvae by preventing them from developing into adult fleas. These two ingredients together are what allow Frontline Plus to end current flea infestations and prevent new ones from happening.

Brand Name

Frontline Plus

Manufacturer

Merial

Active Ingredients

Frontline Plus for Dogs (all sizes)

Ingredients (per applicator) Amount
Fipronil 9.8%
(S)-methoprene 8.8%
Inert Ingredients 81.4%

Frontline Plus for Cats

Ingredients (per applicator) Amount
Fipronil 9.8%
(S)-methoprene 11.8%
Inert Ingredients 78.4%

Common Misspellings

Fontline Plus, Fronline Plus, Front Line Plus, Frontline Pluss, Frontlineplus, Frontine Plus

Warranty and Manufacturer Information

Merial Limited. 3239 Satellite Blvd., Duluth, GA 30096-4640

Frontline Plus for Dogs & Puppies NAC No.: 1111014.3

Frontline Plus for Cats & Kittens NAC No.: 1111013.4

The above is provided for information purposes only and should not be used for the diagnosis or treatment of any condition. This information does not cover all possible variables, conditions, reactions, or risks relating to any topic, medication, or product and should not be considered complete. Certain products or medications may have risks and you should always consult your local veterinarian concerning the treatment of your pet. Any trademarks are the property of their respective owners.

How to Use Frontline Plus

Directions

Frontline Plus for Dogs is available in four different colors for dogs of the following weight brackets:

  • Frontline Plus Orange is for small dogs weighing 0-22 lbs.
  • Frontline Plus Blue is for medium dogs weighing 23-44 lbs.
  • Frontline Plus Purple is for large dogs weighing 45-88 lbs.
  • Frontline Plus Red is for extra large dogs weighing 89-132 lbs.

For dogs weighing over 132 lbs., use the appropriate combination of products. Frontline Plus for Cats can be used on cats of all weights as long as they are age 8 weeks or older.

Applying Frontline Plus

  1. Remove the applicator: Lift and remove the plastic tab and expose the foil. Peel away the foil backing or use scissors to open.
  2. Open applicator: Hold the applicator upright with the foil side toward you. Snap the applicator tip.
  3. Apply Frontline Plus: Remove your pet's collar and part their hair between the shoulder blades. Place the tip just above the skin and squeeze. Apply the entire contents in a single spot on your pet's skin. Make sure not to apply on top of the haircoat. Avoid contact with the wet, treated spot until dry. Only one applicator per treatment is necessary.

The manufacturer recommends you reapply Frontline Plus every 30 days. It will remain effective even after bathing, swimming, or exposure to direct sunlight.

Side Effects

Some animals may experience sensitivities to the ingredients in Frontline Plus, though this is rare. Some may experience temporary irritation at the site of application. If signs persist or become more severe in a few days after applying Frontline Plus, seek immediate veterinary care. If your pet has an unusual reaction, talk to your veterinarian before repeating treatment with Frontline Plus. The manufacturer may be reached 1.800.660.1842 for 24-hour assistance.

Cautions

Read the manufacturer's instructions and product label before use. Do not use a product labeled for dogs on cats or vice versa.

Talk to your veterinarian before using Frontline Plus on your dog or cat if they are medicated, debilitated, or aged. There may be unexpected interactions. If irritation at the site of application persists, seek veterinary care.

Frontline Plus is harmful if swallowed and can cause eye irritation. Avoid contact with your skin, eyes, or clothing while applying it on your pet. Wash thoroughly with soap and water after handling Frontline Plus.

Storage

Do not use or store near heat or open flames. Do not contaminate water, food, or feed by storage and disposal. Keep unused Frontline Plus applicators in the original container only, and keep them out of reach of children and animals. Never place unused product down any indoor or outdoor drain.

Frequently Asked Questions about Frontline Plus

What is Frontline Plus and how does it work?

Frontline Plus is a monthly, topical flea and tick preventative for dogs and cats that are older than 8 weeks of age. You apply it to your pet's skin every 30 days where its two ingredients--Fipronil and (S)-methoprene--go to work killing fleas, ticks, and chewing lice. The oils in your pet's hair and skin distribute Frontline Plus all over your pet's body for one month.

What are the side effects?

Individual animals may have sensitivities to any pesticide product. Some pets may experience minor, temporary irritation at the site of application. If signs persist or worsen over the next few days, seek immediate veterinary care. If your pet has an unusual reaction to the initial application of Frontline Plus, consult with your veterinarian before using the product again. Also, certain medications can interact with Frontline Plus, so consult with your veterinarian first if your pet is on medications, debilitated, or aged.

What should I do if my pet is showing signs of an overdose or if I accidentally gave them a double dose?

If you suspect an overdose in your pet, you should seek veterinary care immediately. If you accidentally gave your pet a double dose of Frontline Plus, you should contact your veterinarian.

Does this product need a prescription?

No. Frontline Plus is an over-the-counter product and does not require a veterinary prescription.

How long does Frontline Plus take to kill fleas?

Studies have shown that Frontline Plus kills 100% of adult fleas within 24 hours. It also kills all ticks on your pet within 48 hours.

Which Frontline Plus should I buy for my dog?

Frontline Plus for Dogs is sold in four different sizes for dogs of the following weights: 0-22 lbs. (Orange), 23-44 lbs. (Blue), 45-88 lbs. (Purple), and 89-132 lbs. (Red). If your dog weighs more than 132 lbs., use the appropriate combination of products to equal their weight. Feline Frontline Plus can be used on cats of all sizes.

VetDepot sells all sizes of Frontline Plus in 3 month, 6 month, and 12 month supplies.

Do fleas and ticks have to bite my pet for Frontline Plus to work?

No. Frontline Plus kills fleas and ticks that come in contact with it on your pet's haircoat.

Can I use Frontline Plus if my pet is on medication?

Ask your veterinarian about possible drug interactions before applying Frontline Plus to your cat or dog.

Can I use Frontline Plus if I've already used another flea and tick control product on my pet?

Before using another flea and tick preventative, consult with your veterinarian.

How does Frontline Plus kill fleas before they can lay eggs on my pet?

Adult fleas require 24 to 36 hours on your pet before they can lay eggs. Because Frontline Plus kills adult fleas within 24 hours of application, they will die before they can lay eggs.

I just applied Frontline Plus, so why am I seeing more active fleas on my pet?

The Fipronil in Frontline Plus works on the fleas' nervous systems. By blocking certain stabilizing ions, the fleas die of hyperstimulation, and as they die, they rise to the top of your pet's haircoat. If you start seeing more fleas after treating your pet with Frontline Plus, this is a good thing.

I already treated my pet with Frontline Plus. Why am I still seeing fleas in my home?

The fleas you're seeing most likely came from flea eggs that were deposited in your home before you began using Frontline Plus. Using Frontline Plus monthly will help break the indoor flea's life cycle. If you have a heavy flea infestation in your home, you may need to use indoor flea control products like Adams Plus Foggers or Virbac Knockout ES Area Treatment.

How long after applying Frontline Plus can my pet take a bath or go swimming?

Frontline Plus is effective for 30 days, even after swimming or bathing. After applying Frontline Plus, make sure you wait 24 hours before allowing your pet to get wet. If you need to apply this product right after a bath, make sure your pet is completely dry first.

Does Frontline Plus kill any other pests besides fleas and ticks?

Frontline Plus for Dogs & Cats also kills chewing lice.

Can I use Frontline Plus on other animals besides cats or dogs?

No. Only use Frontline Plus on the animal specified on the packaging. Do not use a Frontline Plus product for dogs on a cat because the products are based on the species of animal as well as its weight.

Can I use Frontline Plus on myself to treat fleas?

No. Frontline Plus is formulated only for cats and dogs. Do not use on humans.

Can I reapply Frontline Plus before the 30-day interval is up?

Do not reapply Frontline Plus before the 30-day interval has passed. This product is designed to keep working for the full 30 days.

What if my dog is still growing? Can I give them a higher dose?

You should consult with your veterinarian about what Frontline Plus weight range they'd recommend for your pet. If you use the higher dose, it could result in an overdose.

Do I still have to use a flea preventative during the winter months?

Even in colder climates fleas are a threat year-round. Flea pupae are able to survive very cold conditions, and many areas in the United States do not get cold enough to completely wipe out adult fleas. Fleas are also able to hide in the cracks and corners of your home. If just one of those fleas lays eggs on your pet, a new infestation can begin. It's much simpler and safer to continue using products like Frontline Plus all year.

Does this product repel mosquitoes?

No. Frontline Plus does not repel mosquitoes. A similar product, K9 Advantix II, does repel mosquitoes, but it is only for use on dogs.

Can I use Frontline Plus with Trifexis?

While Trifexis is used to protect against heartworms, it also offers protection against fleas. You should consult your veterinarian before switching your pet to or from Trifexis and should not use Trifexis and Frontline Plus together without your veterinarian's approval and instructions.

Can I use Frontline Plus with Diatomaceous Earth?

You should consult your veterinarian before using Diatomaceous Earth and Frontline flea control together.

Does Frontline Plus have an expiration date?

The manufacturer, Merial, reports that Frontline Plus will not expire as long as you keep it at room temperature and sealed in its original packaging.

Will Frontline Plus work on ear mites too?

No. Frontline Plus does not treat ear mites in dogs and cats. We carry products like Sentry HC Earmite Free and Otomite Plus to treat your pet's ear mites.

Will Frontline Plus get rid of bed bugs?

No. Frontline Plus is not formulated to repel or kill bed bugs.

Can Frontline Plus make a dog drowsy?

Drowsiness is not one of the reported potential side effects. Consult with your veterinarian.

Is this product waterproof?

Yes. Frontline Plus is still effective even after swimming or bathing. Make sure to wait 24 hours after application before your pet gets wet.

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