Canine Spectra 9, Single Syringe is an annual booster that protects dogs against Distemper, Adenovirus, Parainfluenza, and Parvo. It's also effective against Lepto and canine hepatitis. Please Note: We are unable to ship this product to the following states: CT, DE, IL, MN, NH, NJ, and NY. This product requires overnight expedited shipping and ships Monday through Thursday. During summer months, the purchase of 1 or 2 additional ice packs is advised.