Gallbladder and Liver Disease Pet Medications

Ursodiol (generic Actigall) is a bile acid medication for the treatment of certain gallbladder and liver diseases in pets. This medication may also help treat cholesterol-containing gallstones. Ursodiol does not treat calcified gallstones. Although Ursodiol is not FDA-approved for use in cats and dogs, it is commonly prescribed for these animals.

Ursodiol improves the flow of bile through the gallbladder ducts and into the intestines to effectively prevent a toxic build up of bile. This treats liver and gallbladder disease and restores healthy liver function in dogs and cats.

Benefits of Ursodiol:

  • Treats cholesterol-containing gallstones
  • Generally well-tolerated
  • Treats liver disease and gallbladder disease in both cats and dogs
  • May also help treat chronic active hepatitis and cirrhosis
  • Prolongs and improves quality of life in pets

Dosages of this medication vary depending on the individual animal and the severity of symptoms. Consult your veterinarian for dosing information.


  1. Give Ursodiol with food, preferably with an oily or fatty meal.
  2. Administer the dose exactly as prescribed by your veterinarian. Do not increase or decrease the dosage without veterinarian approval.
  3. Wash your hands after administering this medication.

Frequency of Use:

Ursodiol is usually given once or twice per day. You may need to give your pet this medication for a long period of time. Do not stop using this medication until your veterinarian instructs you to do so.


Store Ursodiol in its original, tightly closed container. Store at room temperature, away from moisture, light, and heat. Do not use beyond the expiration date.

It is a violation of Federal Law to use this product in a manner inconsistent with its labeling.

Ursodiol, a bile acid, treats liver disease in dogs and cats to improve and maintain health. It is especially effective against liver disease resulting from bile toxicity and also treats gallstones that contain cholesterol. Ursodiol works by decreasing cholesterol production in the liver and reducing cholesterol absorption by the animal's intestines.

Active Ingredients: Ursodiol 300 mg

Other Ingredients: Colloidal silicon dioxide, magnesium stearate and starch (corn). Gelatin capsules contain gelatin and titanium dioxide. The capsules are printed with edible ink containing black iron oxide.


Keep this product out of reach of children and animals. Do not use or store in or near open flame or heat.

Ursodiol is intended for use in cats and dogs only. Do not use in guinea pigs, rabbits, or other animals.

CAUTION: Ursodiol may cause vomiting, diarrhea, jaundice or depression in animals. Contact your veterinarian immediately if your pet develops severe diarrhea while using this medication.

Do not give this medication to animals with a known or suspected allergy to it or to other bile acids. Use cautiously in animals with bile duct obstruction, pancreatitis, or inflammation of the bile ducts or gallbladder.

Do not give this medication at the same time as acetaminophen. Tell your veterinarian before beginning treatment with this medication if your dog or cat is currently taking any medications or supplements. Antacids with aluminum and cholestyramine resin may make Ursodiol less effective.

It is not know if Ursodiol is safe for use in pregnant or lactating animals.

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