BRD Treatment Medication

Micotil is a Tilmicosin injection that is used to treat Bovine Respiratory Disease (BRD) in cattle. Tilmicosin is an antibiotic with spectrum activity against gram-positive and certain gram-negative microorganisms.

Micotil 300 treats and controls bovine respiratory disease (BRD) in cattle and ovine respiratory disease (ORD) in sheep. It is cost-effective for individual and mass use. Micotil 300 works rapidly and its effects are long lasting, with a single dose working for 3 days.

Benefits of Micotil 300:

  • Treats bovine and ovine respiratory disease (BRD and ORD)
  • Helps prevent outbreaks of these ailments
  • A sensible choice for individual pull-and-treat use and for metaphylaxis
  • Highly effective
  • Long-lasting antibiotic action, with 1 dose treating the infection for 3 days
  • Minimizes re-pulls

Read label instructions and precautionary statements and the accompanying literature before use.

Follow the specifications of your veterinarian's prescription.


  1. Give 1.5 mL per 100 lbs. of body weight (10 mg per 2.2 lbs. of body weight).
  2. Administer only via subcutaneous injection. Do not administer with an automatically powered syringe.
  3. Do not administer more than 15 mL in a single injection site.
  4. If possible, inject under the skin on the neck. Otherwise, inject under the skin behind the shoulders and over the ribs.

Frequency of Use:

One dose lasts for 3 days. Use exactly as prescribed.

If no improvement is seen within 48 hours, contact your veterinarian for reconsideration of the diagnosis and course of treatment.


Keep out of reach of children and animals.

Store Micotil 300 at temperatures no higher than 86 degrees F. Protect from direct sunlight.

It is a violation of Federal Law to use this product in a manner inconsistent with its labeling.

Tilmicosin, the active ingredient in Micotil 300, is an antibiotic in the macrolide class. It is predominantly effective against gram-positive bacteria, but also has action against some gram-negative bacteria.

Micotil 300 Ingredients (per mL): tilmicosin 300 mg, USP as tilmicosin phosphate in 25% propylene glycol, phosphoric acid as needed to adjust pH and water for injection, Q.S.


Keep Micotil 300 out of reach of children and animals. Do not use or store in or near open flame or heat.

Micotil 300 is only intended for use in cattle and sheep. Do not administer to other species. Not for use in humans. Administration to other animals is associated with severe adverse reactions, including fatalities in swine, horses, goats, non-human primates, and humans.

For subcutaneous injection only. Intravenous injection will result in death. Do not administer via any other route besides subcutaneously.

Use exactly as prescribed by your veterinarian.

Read all accompanying literature prior to use.

CAUTION: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian.

Avoid contact with eyes.

Use extreme caution to prevent accidental self-injection. In the event of accidental injection in a human, apply ice to the site of injection and contact a physician or poison control center immediately.

Note to physicians: The cardiovascular system is the target of toxicity and should be closely monitored. Such toxicity may be caused by calcium channel blockade.

If improvement is not seen within 48 hours, consult your veterinarian for reconsideration of the diagnosis and treatment plan.

The safety of Micotil 300 in pregnant, nursing, and breeding animals has not been proven.

The safety of Micotil 300 in sheep weighing less than 33 lbs. has not been established.

Not for use within 28 days of slaughter. Not for use in female dairy cattle 20 months of age or older. Not for use in lactating ewes if the milk is intended for human consumption.

Do not administer Micotil 300 with an automatically powered syringe.

Swelling may occur at the site of injection. It is typically mild and transient.

Micotil 300 is not generally associated with side effects at recommended doses. Individual sensitivities may still occur. Consult your veterinarian if you observe any adverse effects in an animal.

Ask your veterinarian before using Micotil 300 concomitantly with any other drug or supplement.

To report adverse effects, access medical information, or obtain additional product information, call 1-800-428-4441.

Warranty and Manufacturer Information:

NADA 140-929, Approved by FDA


Elanco®, Micotil® and the diagonal color bar are trademarks of Eli Lilly and Company.

Manufactured for: Elanco Animal Health, A Division of Eli Lilly and Company, Indianapolis, IN 46285, USA

Revised JANUARY 2006

Literature for this product should be attached. If it is missing call 1-800-428-4441.

NAC No.: 10310056

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