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Chlorpheniramine Maleate 4 mg, 100 Tablets
Retail: $22.99
Retail: $22.99
Price: $16.15 Save: $6.84

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Availability: Over the Counter
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Availability: Over the Counter
Generic Mfr Item #: 1017591 -

Antihistamines for Pets

Chlorpheniramine is an antihistamine for pets and people that is used to treat allergic reactions from snake bites, vaccination reactions, atopic dermatitis, atopy, and more.

Chlorpheniramine is an antihistamine primarily used in cats, dogs, and ferrets. It is indicated to remedy standard allergy symptoms and to treat some acute inflammatory allergic conditions. Chlorpheniramine is used for reactions to vaccinations and blood transfusions, insect bites and stings, snakebites, to soothe itchy skin, and for a variety of other related purposes.

Benefits of Chlorpheniramine:

  • Treats allergic reactions to contact, inhaled, and pharmaceutical triggers
  • Counteracts reactions to blood transfusions and vaccinations
  • Eases symptoms resulting from snake bites and insect bites and stings
  • Provides relief from itching skin
  • Helps prevent injury and infection from excessive scratching
  • Can temper chronic inflammatory symptoms associated with mast cell tumors
  • Sometimes used to help manage feline asthma
  • Anti-nausea properties that are occasionally applied to prevent or treat motion sickness
  • Offers fast relief, working within 1 hour
  • One of the most effective antihistamines in cats

For animal use only. Do not allow children to administer this antihistamine.

Antihistamines may be more effective when taken in conjunction with an omega-3 fatty acid supplement.

Review package directions and warnings.

The following directions represent standard uses, but dosages may vary. Use as directed by your veterinarian.


  1. Give dogs 1 to 2 tablets (4 to 8 mg) every 8 to 12 hours. For itching skin allergies, give dogs 0.18 to 0.36 mg per pound of body weight every 8 to 12 hours. As a mild sedative, give dogs 0.1 mg per pound of body weight every 8 to 12 hours.
  2. Give cats ½ to 1 tablet (2 to 4 mg) every 12 to 24 hours. For itching skin allergies, give cats 2 to 4 mg twice daily. As a mild sedative, give cats 1 to 2 mg every 12 to 24 hours, or a higher dose of 2 to 4 mg every 12 to 24 hours.
  3. Give ferrets 1/2 to 1 tablet (2 to 4 mg) per pound of body weight every 8 to 12 hours.

Frequency of Use:

Doses are typically given to dogs and ferrets 2 to 3 times per day, and to cats 1 to 2 times per day.


Keep out of reach of children and animals.

Store Chlorpheniramine in its original container, tightly sealed, at room temperature. Protect from moisture (keep out of bathroom) and do not freeze.

It is a violation of Federal Law to use this product in a manner inconsistent with its labeling.

Chlorpheniramine blocks the effects of histamine in the body. This makes it useful in suppressing inflammatory allergic responses to various triggers. Chlorpheniramine is not FDA-approved for use in cats and dogs; however, it is a common veterinary practice to use it off-label in these animals.

Chlorpheniramine is sold over the counter.

Chlorpheniramine (chlorpheniramine maleate)

Chlorpheniramine Active Ingredient (per tablet): Chlorpheniramine maleate 4 mg

Chlorpheniramine Inactive Ingredients: D&C Yellow #10, lactose, magnesium stearate, microcrystalline cellulose, pregelatinized starch


Keep this product out of reach of children and animals. Do not use or store in or near open flame or heat.

For animal use only.

Although Chlorpheniramine is sold without a prescription, consult your veterinarian before use and follow provided recommendations for safe and effective administration.

CAUTION: May cause drowsiness. Other possible side effects include diarrhea, vomiting, decreased urine output, diminished appetite, and dry mouth.

Chlorpheniramine interferes with allergic skin testing. Ask your veterinarian about the need to withhold administration before an appointment.

Not for use in pregnant or lactating animals.

Not for use in animals with a urinary, stomach, or intestinal obstruction, or in those with glaucoma, prostate disease, heart disease, hypertension, or hyperthyroidism.

Use with caution in animals taking phenothiazines or other central nervous system depressants.

Do not use in animals with a hypersensitivity to chlorpheniramine or similar medications. Seek emergency veterinary treatment for an allergic reaction. Some signs include facial swelling, itching, hives, rash, difficulty breathing, seizures, shock, cold limbs, and coma.

Do not use products that combine an antihistamine with acetaminophen or caffeine in animals.

Do not use concurrently with any tranquilizer.

Antihistamines can interfere with the anticoagulation effects of warfarin and heparin.

Do not use concurrently with any monoamine oxidase inhibitors (MAOIs). Tell your veterinarian what drugs and supplements your pet takes. Check before administering any new medications or supplements while your pet is taking Chlorpheniramine.

Contact your veterinarian immediately in the event of an overdose. Some signs include drowsiness, hyperactivity, seizures, difficulty breathing, coma, and death.

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