Zymox Topical Cream With Hydrocortisone 1.0%, 1 oz treats skin infections in dogs and cats caused by susceptible bacteria, fungi, and viruses. Zymox Cream uses a combination of powerful natural enzymes to kill the microbes and hydrocortisone steroids to fight pain and inflammation. Can be used to treat hot spots, pyoderma, dermatitis, anal sac abscesses, and more.