Adequan for Dogs & Horses

Dog and Horse Injectable Solution for Joint Pain

Adequan Canine is an injectable solution used to treat arthritis, joint pain and inflammation, and joint degeneration in dogs. Not only does it control symptoms associated with aging and arthritic joints, it also supports regrowth of cartilage and increases synovial fluid in the joints.

Benefits of Adequan Canine:

• Provides relief from the pain and inflammation associated with arthritis and joint degeneration
• Helps repair damaged joints by increasing cartilage and synovial fluid
• Useful as a postoperative administration when the joints are affected
• Enhances your dog's quality of life
• Promotes continued mobility and related health benefits
• Provides relief within hours and often brings about general improvement within 4 weeks
• Prescription-strength relief and treatment for your dog

Adequan I.A. Equine and Adequan I.M Equine are joint relief medications used in aging and arthritic horses. These products treat joint dysfunction and associated lameness by slowing the degeneration of joints and improving their function. They accomplish this by promoting cartilage regrowth and thicker synovial fluid.

Benefits of Adequan Equine Solutions:

• Reduce pain and inflammation associated with aging and degenerating joints
• Effective against non-infectious degenerative and traumatic arthritis
• Support recovery following surgery affecting the joints
• Aid the carpal and hock joints
• Treat symptoms and help heal the underlying problems of cartilage and synovial fluid loss
• Enhance a horse's comfort and allow for more mobility
• Reduce the likelihood of obesity or other health problems stemming from lack of activity
• Work quickly to provide relief and start improving joint function

Adequan Canine is intended for use in dogs. Do not use in other animals. Do not administer to any animal for which it was not prescribed by a veterinarian. Not for use in humans.

Do not permit children to administer Adequan Canine.

Review all manufacturer instructions and warnings prior to use. Use exactly as prescribed by your veterinarian.

Directions for Adequan Canine:

1. Sterilize a syringe and the site of injection with a topical disinfectant.
2. Dose your dog at 2 mg per pound of body weight (1 mL per 50 lbs.).
3. Administer the injection intramuscularly.
4. Give your dog the injection twice per week for up to 4 weeks. Do not administer a regimen of more than 8 injections.

Directions for Adequan I.A.:

1. Sterilize the syringe and shave and sterilize the site of injection.
2. Give the horse 1 vial (250 mg) once per week for 5 weeks.
3. Make the injection intra-articularly in a carpal joint as instructed by your veterinarian.

Directions for Adequan I.M.:

1. Sterilize the syringe and the site of injection.
2. Give the horse 500 mg every 4 days for a period of 28 days.
3. Make the injection intramuscularly as instructed by your veterinarian.

Frequency of Use:

The standard schedule of administration for Adequan Canine solution is twice weekly for up to 4 weeks.

In the event of a missed dose, administer it upon remembering it. However, if it is almost time for the next dose, just wait. Never administer a double dose of this medication.

Storage:

Keep out of reach of children and animals.

Store Adequan Canine in its original vial between 64 and 77 degrees F.

It is a violation of Federal Law to use this product in a manner inconsistent with its labeling.

Adequan Canine (polysulfated glycosaminoglycan)

Adequan Canine Solution is sold in 5 mL preserved multiple dose vials providing 100 mg/mL polysulfated glycosaminoglycans.

Active ingredients: Polysulfated Glycosaminoglycan 100 mg, benzyl alcohol (a preservative) 0.9% v/v, water

Inactive ingredients: Sodium hydroxide and/or hydrochloric acid added when necessary to adjust pH. Sodium Chloride may be added to adjust tonicity

Adequan I.A., I.M. Equine (polysulfated glycosaminoglycan)

Adequan I.A. is sold in 6-packs of 1-mL vials. Each vial contains 250 mg polysulfated glycosaminoglycan.

Adequan I.M. is sold in 5 mL and 50 mL vials containing 100 mg polysulfated glycosaminoglycan per mL.

Adequan I.A. Ingredients (per mL): Polysulfated Glycosaminoglycan 250 mg and Water for Injection q.s. Sodium Hydroxide and/or Hydrochloric Acid added when necessary to adjust pH.

Adequan I.M. Ingredients (per mL): Polysulfated Glycosaminoglycan 100 mg, Benzyl Alcohol 0.9% v/v as a preservative, and Water for Injection q.s. Sodium Hydroxide and/or Hydrochloric Acid added when necessary to adjust pH.

Warnings:

Keep this product out of reach of children and animals. Do not use or store in or near open flame or heat.

Adequan Canine is intended only for use in dogs. Do not use in humans or in other animals.

Use this medication as prescribed.

CAUTION: The safety of Adequan Canine in pregnant, lactating, and breeding dogs has not been established.

Use with caution in animals with liver or kidney disease and in those with coagulation or clotting disorders.

Overdose with Adequan Canine is rare. Indications of toxicity include joint pain, swelling, and lameness. Seek immediate veterinary care.

Side effects are uncommon and generally mild. They may include pain or irritation at the site of injection, diarrhea, clotting impairment, or other adverse reactions. Consult your veterinarian about any observed side effects.

Not for use in dogs with hypersensitivity to polysulfated glycosaminoglycan. Facial swelling, itching, cold limbs, hives, rash, seizures, shock, and coma are common signs of an allergic reaction. Seek emergency veterinary treatment.

Talk to your veterinarian before using any other drugs or supplements while your dog is taking Adequan Canine.

Warranty and Manufacturer Information:

NDC 10797-975-02

Manufactured by: LUITPOLD PHARMACEUTICALS, INC., Animal Health Division, Shirley, NY 11967

(631) 924-4000

1-800-458-0163

Marketed by: NOVARTIS ANIMAL HEALTH US, INC., Greensboro, NC 27408

NADA 141-038, Approved by FDA

Made in U.S.A.

Rev. 1/04

IN975

MG #12417

NAH/ADQ/VI/1

NAC No.: 10390002