This is the only other heartworm preventative that also has parasitic worm protection as well as flea and tick protection. The only other being Sentinel (White Label). However Sentinel is out of production due to a manufacturer recall, thus the only viable choice is Trifexis. It is seemingly the most expensive heartworm preventative with Sentinel in tow, however when you consider the protection level it provides in one convenient pill, it is actually very cost effective. Since purchasing separate flea and tick protection will easily exceed the costs of Trifexis.
Yet the most important factor here is providing optimal protection for your loved member of the family. And there is no cost that can be placed on that. Please consider that treating heartworm is far more costly and dangerous to the wellbeing of your loved one. And Vetdepot does have the best pricing on both Sentinel and Trifexis.
We switched as Sentinel is out of production temporarily and with a little peanut butter to coat the pill, there was little issue to have our dogs swallow them (we have four large dogs). The pills like sentinel are actually very small, which is an added benefit when you consider how large some of the other pills are. It does have a strong earth scent, like wild mushrooms, however as stated, a little cheese or peanut butter can easily mask the scent.
Highly recommended, and well worth the protection and peace of mind knowing you are providing them the very best possible protection.