Skin and Ear Infection Treatment for Pets

Tresaderm is a topical antibiotic, antifungal, and anti-inflammatory agent. It is used in the treatment of ear and skin infections and some inflammatory skin disorders caused or aggravated by bacteria or fungus. Tresaderm may be used for acute and chronic conditions. This is a prescription-strength medication.

Tresaderm treats a variety of bacterial, fungal, and inflammatory skin and ear disorders and infections in cats and dogs. It is effective against acute and chronic conditions. It provides relief from symptoms associated with inflammation while remedying infections and dermatological problems. Tresaderm is effective and fast acting.

Benefits of Tresaderm:

  • Treats bacterial and fungal skin and ear infections
  • Reduces inflammation associated with infections and otitis externa
  • Works on chronic and acute conditions
  • Provides full treatment in one week or less
  • Easily applied topical application
  • Liquid form and bottle dropper facilitate application in the ears

Read all label directions and warnings before use.

Use exactly as prescribed by your veterinarian.


  • Clean the affected site and remove any crusty buildup. Remove any wax, debris, or foreign matter from the ear canal for otic use.
  • Moisten skin lesions well with Tresaderm, using 2 to 4 drops per square inch as prescribed twice daily.
  • Instill 5 to 15 drops in the ear twice daily as prescribed for otic use.
  • Return bottle to the refrigerator.

Frequency of Use:

Typical usage requires 2 applications per day. Do not use for longer than 1 week.

Apply a forgotten dose as soon as you remember it. If it is almost time for the next dose, wait and resume the normal schedule then. Do not apply a double dose of Tresaderm.


Keep out of reach of children and animals.

Store Tresaderm in the refrigerator. Do not freeze.

It is a violation of Federal Law to use this product in a manner inconsistent with its labeling.

Neomycin, one of Tresaderm's active ingredients, is a potent antibiotic that is effective against many gram-positive and gram-negative bacteria. Thiabendazole, another active ingredient, kills or inhibits fungi. Tresaderm also contains dexamethasone, a corticosteroid that reduces the body's inflammatory response.

Tresaderm requires a prescription from your veterinarian.


Tresaderm Active Ingredients (per mL): Thiabendazole 40 mg, dexamethasone 1 mg, neomycin (from neomycin sulfate) 3.2 mg

Tresaderm Inactive Ingredients: glycerin, propylene glycol, purified water, hypophosphorous acid, calcium hypophosphite, about 8.5% ethyl alcohol, about 0.5% benzyl alcohol


Keep Tresaderm out of reach of children and animals. Do not use or store in or near open flame or heat. Tresaderm should be kept in the refrigerator.

Tresaderm is only for use on cats and dogs. Do not apply to other species. Not for use on humans.

For topical use only.

Follow the instructions provided by your veterinarian's prescription.

CAUTION: Avoid contact with the eyes. If contact occurs, flush eyes well with clean water. Consult your veterinarian if irritation persists.

Rarely, dogs may be sensitive to neomycin and develop erythema at the site of application, generally lasting 24 to 48 hours.

Temporary irritation may result with application to fissured or denuded areas. Expressions of pain can be expected to last 2 to 5 minutes.

Not for use in pets with a hypersensitivity to any of the included ingredients.

Not for use for longer than 1 week.

Although topical applications of corticosteroids are not generally associated with systemic reactions, the possibility must be considered with prolonged or repeated use. If signs of dehydration are observed, discontinue use and consult your veterinarian.

Tell your veterinarian if your pet is already taking any antibiotic, antifungal, or anti-inflammatory product. Consult your veterinarian prior to concurrent administration of any other drugs or supplements.

Side effects are related to individual ingredients. Ask your veterinarian about any observed adverse reactions in your pet.

Warranty and Manufacturer Information:

TRESADERM is a registered trademark of Merial.

Marketed by Merial Limited, Duluth, Georgia 30096-4640

(Merial Limited: Registered in England and Wales [Reg. No. 3332751] with registered offices at 27 Knightsbridge, London, SW1X 7QT, England and domesticated in Delaware, USA as Merial LLC).

2000 Merial. All rights reserved.

January 2002


NAC No.: 11110793

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Tresaderm, 15 mL
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