I tried this on its own and it did not seem to do much, but then recently I gave it another shot now that my dog is taking another supplement and getting injections from the vet. It seems to boost the effectiveness of her current treatment plan.
I have been using this for my two dogs now for about 10 months and they seem to be more active and get around better. They are 7 years old and are large breed dogs weighing over 100lbs. I find that it is the best dosage for large dogs for the price.