Mineralocorticoids for Dogs

Percorten-V is the only FDA-approved pet medication for treating Canine Addison's Disease, a condition characterized by underperforming adrenal glands. The active ingredient in Percorten-V, desoxycorticosterone pivalate (DOCP), functions as a replacement therapy for mineralocorticoid deficiency. Percorten-V for dogs is available as an injectable suspension.

Percorten-V is an injectable, FDA-approved prescription medication for treating mineralocorticoid deficiency in dogs with primary adrenocortical insufficiency, or Canine Addison's Disease. Percorten-V is a corticosteroid.

Benefits of Percorten-V:

  • Enhances your dog's quality of life
  • Extends your dog's life expectancy
  • Eases symptoms of Canine Addison's Disease, such as lethargy, weakness, depression, weak pulse, susceptibility to dehydration, low blood sodium levels, and high blood potassium levels
  • Promotes electrolyte balance
  • Well-tolerated by most dogs
  • Rarely causes side effects
  • A single injection lasts three to four weeks

For Use In: Dogs of all sizes

Percorten-V is sometimes used off-label to treat Addison's Disease in cats. Consult your veterinarian about such a use if your cat has this condition. Do not administer Percorten-V injections to an animal to which it was not prescribed.

Keep out of reach of children. Do not allow children to administer Percorten-V. Review package directions and precautionary statements before use. Follow prescription precisely.

Injections are made intramuscularly, not intravenously. Ask your veterinarian for instructions on administering Percorten-V.


  1. Shake individual vial vigorously before opening.
  2. Administer Percorten-V injections exactly as instructed by your veterinarian.
  3. Typical dosage begins at 1 mg per lb. Dosages are adjusted by your veterinarian according to electrolyte levels in the blood.
  4. Inject the medication into the dog's muscle, and never into a vein. Injection of Percorten-V into a vein can cause acute collapse and shock. This requires immediate treatment with intravenous fluids and glucocorticoids.

Frequency of Use:

Administer Percorten-V as prescribed. Usually, injections are given once every 25 days. Percorten-V does not cure Canine Addison's Disease, so treatments are continued for the animal's lifetime. Contact your veterinarian if you miss a dose. Do not administer a double dose.


Store in original container and out of reach of children and animals.

Store Percorten-V at room temperature, ideally between 56 and 89 degrees F. Protect from light and do not allow product to freeze.

It is a violation of Federal Law to use this product in a manner inconsistent with its labeling.

The desoxycorticosterone pivalate in Percorten-V replaces depleted mineralocorticoid steroids in dogs with Canine Addison's Disease to promote healthy electrolyte balances and prevents buildup of toxic substances in their bloodstream.

Percorten-V is available by prescription from your veterinarian.

Percorten-V (desoxycorticosterone pivalate)

Injectable Suspension Ingredients: Multiple-Dose Vials, 4 ml, each ml containing 25 mg desoxycorticosterone pivalate (DOCP), 10.5 mg methylcellulose, 3 mg sodium carboxymethylcellulose, 1 mg polysorbate 80, and 8 mg sodium chloride with 0.002% thimerosal added as preservative in water for injection. Packed one vial per carton.


Keep this product out of reach of children and animals. Do not use or store in or near open flame or heat.

Do not mix Percoten-V with other injectable medications.

Percoten-V is intended only for use in dogs with Canine Addison's disease. It is not a cure, but a medication for managing symptoms.

CAUTION: Because of the risk of interactions, consult your veterinarian before giving your dog vitamins or supplements, diuretics, insulin, digitalis, aspirin, amphotericin B.

Side effects of Percorten-V include diarrhea, loss of appetite, vomiting, weakness, incontinence, and weight loss. Pain, irritation, infection, or abscesses at the injection site are also possible. Consult your veterinarian as soon as possible if you notice side effects in your dog.

Intravenous (IV), rather than intramuscular (IM) injection requires prompt medical treatment.

Do not administer to pregnant animals unless benefits outweigh the risks. Percorten-V is not for use in dogs with congestive heart failure, kidney disease, or edema (swelling). Not for use in animals allergic to it or drugs similar to it.

Increased drinking and urination, weight gain, edema, and high blood pressure may indicate an overdose. Consult your veterinarian right away if you suspect or know of an overdose.

Rule out primary renal disease before starting therapy with Percorten-V.

Warranty and Manufacturer Information:

Seller makes no warranty, expressed or implied, concerning the use of this product other than indicated on the label. Buyer assumes all risk of use and handling of this material when such use and handling are contrary to label instructions.

Manufactured for: Novartis Animal Health US, Inc. Greensboro, NC 27408, USA

NADA # 141-029, Approved by FDA.

© 2001 Novartis




PERCORTEN-V is a registered trademark of Novartis AG.

NAC No.: 11310044

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