Generic Frontline Flea and Tick Control for Dogs and Cats

EctoAdvance is a once-a-month topical flea and tick control pet medication for dogs and cats. EctoAdvance flea treatment contains fipronil which kills fleas, flea eggs, and all stages of ticks, including those that may carry Lyme disease. EctoAdvance is sold in 3, 6, and 12 month packs for dogs weighing 0-22 lbs, 23-44 lbs, 45-88 lbs, 89-132 lbs, and for cats in all weight ranges.

EctoAdvance provides rapid, effective, and comprehensive protection against fleas, ticks, and chewing lice. The product also assists in the control of sarcoptic mange and is safe for use on pregnant, lactating, and breeding dogs.

Benefits of EctoAdvance:

  • Kills all stages of fleas
  • Eliminates existing infestations and prevents new ones
  • Affordable alternative to Frontline Plus
  • Convenient once-monthly dosing
  • Effective against deer ticks, American dog ticks, brown dog ticks, and lone star ticks
  • Eliminates chewing lice infestations quickly
  • Helps clear up sarcoptic mange in dogs
  • Kills adult fleas, larvae, and eggs for up to three months with a single application
  • Kills ticks and chewing lice for up to one month
  • Prevents flea allergy dermatitis
  • Prevents lyme disease transmitted by tick bites

EctoAdvance for Cats offers quick and effective control of fleas, ticks, and chewing lice in a convenient, once-monthly spot treatment. This product is safe for use in pregnant, lactating, and breeding cats and in kittens 8 weeks or older.

Benefits of EctoAdvance for Cats:

  • Rapidly stops existing infestations of fleas, ticks, and chewing lice
  • Kills all stages of fleas, including adults, larvae, and eggs
  • Helps prevent flea allergy dermatitis
  • Fast-acting, long-lasting, and waterproof
  • Prevents lyme disease by keeping ticks away
  • Prevents future infestations from occurring
  • Kills all stages of fleas for up to 6 weeks
  • Kills ticks and chewing lice for up to one month

Do not allow children to apply or handle EctoAdvance.

Read product label carefully before use. Follow all precautionary statements.

Avoid contact with the treated area until it is completely dry.


  1. Remove EctoAdvance applicator from packaging.
  2. Hold the applicator in an upright position and snap the tip while pointing the applicator away from your face and body.
  3. Place the tip of the applicator against your pet's skin, centered between the shoulder blades.
  4. Squeeze the applicator to expel the entire contents to a single spot. Make certain the product is applied to the skin and not to the coat.

Frequency of Use:

Use one applicator each month to eliminate flea, tick, and chewing lice infestations.

Multiple monthly treatments are typically necessary to eliminate mites and treat sarcoptic mange.


Keep unused product in its original container. Keep out of the reach of children and pets.

Dispose of empty containers in the trash. Do not contaminate feed, food, or water by improper storage and disposal of EctoAdvance.

It is a violation of Federal Law to use this product in a manner inconsistent with its labeling.

EctoAdvance contains two active ingredients that work together to protect dogs from flea, tick, and lice infestations. Fipronil collects in your dog's hair follicles where it is continuously released onto the coat and skin to prevent flea infestations. (S)-methoprene is an insect growth regulator that stops the flea and tick life cycle to eliminate existing infestations.

EctoAdvance for Dogs is available over the counter.

EctoAdvance (generic to Frontline Plus)

EctoAdvance Active ingredients: fipronil: 9.8%, (S)-methoprene 8.8%

Inactive ingredients: 81.4%

EctoAdvance for Dogs up to 22 lbs. (0.67 mL)

EctoAdvance for Dogs 23-44 lbs. (1.34 mL)

EctoAdvance for Dogs 45-88 lbs. (2.68 mL)

EctoAdvance for Dogs 89-132 lbs. (4.02 mL)

EctoAdvance for Cats (generic to Frontline Plus)

Active ingredients: fipronil: 9.8%, (S)-methoprene 11.8%

Inactive ingredients: 78.4%


Keep this product out of reach of children and animals. Do not use or store in or near open flame or heat.

EctoAdvance for Dogs is for use on dogs 8 weeks of age and older. Not for cats, rabbits, or other animals. Not for human use.

EctoAdvance for Cats is intended for use in cats and kittens 8 weeks of age and older. Not for use in dogs, rabbits, or other animals. Not for human use.

EctoAdvance is for external use only. Temporary irritation at the application site may occur. Consult a veterinarian if the irritation persists or worsens after several days.

CAUTION: Swallowing this product causes harm. EctoAdvance may cause significant eye irritation. Avoid contact with eyes, skin, and clothing, and wash hands with clean water and soap after each use.

Consult a veterinarian before using this product on aged, debilitated, or medicated dogs. Tell your veterinarian if your dog is currently taking any medications or supplements before beginning treatment with EctoAdvance.

If Swallowed: Call a medical professional or poison control center for immediately treatment advice. Have product label available when calling or seeking emergency treatment. While waiting for medical attention, slowly sip water. Do not induce vomiting unless instructed to do so by a poison control center or doctor.

If in Eyes: Thoroughly flush the affected eye(s) with clean water. Call your doctor promptly for advice.

If on Skin: Wash with soap and clean water and rinse well. Seek help if skin irritation develops or persists.

Warranty and Manufacturer Information:


Seller makes no warranty, expressed or implied, concerning the use of this product other than indicated on the label. Buyer assumes all risk of use and handling of this material when such use and handling are contrary to label instructions.

Distributed by:

Meridian Animal Health

P.O. Box 540160, Omaha, NE 68154


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