Products 1-2 of 2
Depo-Medrol 20 mg/mL, 20 mL
RX item
Retail: $436.99
Retail: $436.99
Price: $397.19 Save: $39.80

use coupon:

estimated: $ 397.19

Availability: Prescription Required
review-star review-star review-star review-star review-star
Availability: Prescription Required
Pharmacia Upjohn Item #: 1010779 -

Depo-Medrol 40 mg, 5 ml
RX item
Retail: $182.99
Retail: $182.99
Price: $166.16 Save: $16.83

use coupon:

estimated: $ 166.16

Availability: Back Order
Availability: Back Order
Zoetis Item #: 1041244 -

Anti-Inflammatory Injection for Pets & Horses

Depo-Medrol corticosteroids are anti-inflammatory pet medications for pets and horses that are injected to treat inflammation caused by disease like arthritis for up to three to four weeks.

Depo-Medrol is a powerful anti-inflammatory steroid medication in injectable form for the treatment of allergic conditions, arthritis, and other problems. It may also be used to suppress the immune system during times of acute illness or in animals suffering from autoimmune disorders. Depo-Medrol is fast acting and works for longer periods than prednisolone or prednisone.

Benefits of Depo-Medrol:

  • Treats bronchial asthma, allergic dermatitis, urticaria, eczema, and other allergic conditions
  • Relief of allergic symptoms may occur as soon as a few hours after injection
  • Reduces pain, stiffness, and lameness associated with a variety of arthritic conditions, bursitis, synovitis, and other problems
  • May prevent vascular collapse and life-threatening inflammatory reactions associated with overwhelming infections
  • More potent than prednisolone and causes fewer side effects

Use this medication only as directed by your veterinarian.

Consult your veterinarian about the proper technique for administering injectable medications.

Dose as prescribed. Do not differ from the dosing schedule given by your veterinarian.

Intramuscular Injection Directions:

  1. Give dogs the dose prescribed by your veterinarian. The typical dose for dogs ranges from 2 mg in miniature breeds to 40 mg in medium breeds. Larger dogs may require even larger doses.
  2. Give cats the amount prescribed by your veterinarian. The usual dose for cats is 10 mg to 20 mg. Dose weekly or as prescribed.
  3. Give horses the amount prescribed by your veterinarian. The typical dose for horses is 200 mg, as needed.

Intrasynovial Injection Directions:

  1. Follow the injection preparation procedure prescribed by your veterinarian.
  2. Dose based on the size of the synovial space and animal.
  3. Give dogs the dose prescribed by your veterinarian. The average dose for a large synovial space is 20 mg.
  4. Give horses the dose prescribed by your veterinarian. The average dose for a large synovial space is 120 mg.

Frequency of Use:

The duration of treatment depends on the animal and condition being treated, the severity of illness, and the individual response. When stopping long-term use, reduce the dose gradually to avoid potentially serious withdrawal effects.


Store Depo-Medrol at room temperature, in a light-resistant and childproof container. Keep away from pets and children.

It is a violation of Federal Law to use this product in a manner inconsistent with its labeling.

Depo-Medrol contains methylprednisolone, a synthetic steroid with anti-inflammatory properties that is a derivative of prednisolone. It works by blocking production of substances in the body that trigger inflammation and allergic reactions.

Ingredients (20 mg per mL): Methylprednisolone acetate 20 mg, Polyethylene glycol 3350 29.6 mg, Sodium chloride 8.9 mg, Myristyl-gamma-picolinium chloride (added as preservative) 0.198 mg

Ingredients (40 mg per mL): Methylprednisolone acetate 40 mg, Polyethylene glycol 3350 29 mg, Sodium chloride 8.7 mg, Myristyl-gamma-picolinium chloride (added as preservative) 0.195mg


Keep this product out of reach of children and animals. Do not use or store in or near open flame or heat.

Depo-Medrol is intended for use in dogs, horses, and cats only. Not for other animals or for humans.

CAUTION: Side effects of Depo-Medrol may include increased thirst, appetite, and urination. Weight gain, diarrhea, behavior changes, vomiting, and panting are other common side effects. Long-term use may result in weakness, muscle loss, diabetes, Cushing's disease, and/or pancreatitis.

Pets taking this medication may experience immune system suppression, putting them at greater risk for infection.

Do not stop giving this medication abruptly. Doing so may cause weakness, vomiting, collapse, or sudden death.

Tell your veterinarian about any over-the-counter or prescription medications your pet is taking before beginning treatment with Depo-Medrol.

Use of Depo-Medrol may cause abnormal levels of thyroid hormone, potassium, hepatic enzymes, or cholesterol. This may affect laboratory testing.

Do not give this medication to animals with tuberculosis, Cushing's syndrome, congestive heart failure, osteoporosis, diabetes, or hypertension without first consulting your veterinarian.

Do not use in pregnant or breeding animals.

Do not use this medication in animals with a known allergy to it or to similar medications.

Warranty and Manufacturer Information:

Caution: Federal (USA) law restricts this drug to use by or on the order of a licensed veterinarian.

NADA No.: 012-204, Approved by FDA

Pharmacia & Upjohn Company, Kalamazoo, Michigan 49001, USA

Revised October 1997

811 350 108


NAC No.: 10490130

Customer ServiceFree Shipping

The VetDepot Difference