I adopted my chocolate lab from the sheriff's pound. He had been neglected, and was 1/2 bald due to flea allergies. Every morning he was diggin', diggin'... We started him on the leading brand of drops applied between the shoulder blades. It seemed to work, until we took a camping trip. He was just COVERED in fleas! Poor boy! Dragged him down to the vet and begged for something more effective. We tried the Comfortis, and that whole flea swarm was dead within the hour. Big Boy has a healthy coat now, and is happy as can be. With VetDepot's prices, there's no reason for us to not keep him dosed every 30 days to keep him healthy. VetDepot did all the legwork with obtaining the prescription from out vet, so it was really easy.