I am a firm believer in generic drugs. I have 2 Great Danes, my boy Bodhi weighing in at 150lbs and is very healthy and then my very special girl Teagan weighing in at 170lbs and who is very problematic. Teagan is special because she started out as a puppy with Salmonella Poisoning and HOD which is a juvenal bone disorder that can cripple your dog if not treated in its early stages. Then at the age of 2 years we move on to Epilepsy than finally massive bone arthritis which is in both knees of her back legs. We always called her our $10,000 dollar Dane who by the way is only 4 years old. At this present time Teagan is on Carprofen and Phenobarbital and has been on many costly drugs for all her ailments. I'm very lucky that I have a veterinarian that can understand how costly it can be to raise Great Danes. Right now the biggest cost is her arthritis meds, she has been on and we have tried to afford to maintain the cost of one or more of these drugs for the past 3 years at different times and stages of her development, Deramaxx, Metacam, Rimadyl, and Novox all at 100mg each 1 1/2 twice a day. Well finally, hundreds of dollars later, we have found the answer to the $10,000 dollar question all because of the great people at VetDepot and their informative website. I FOUND CARPROFEN!!!!!! I called my Vet and said write me a script, of course I got all the warnings from my Vet and rightfully so,"this could make her very sick, not work, and cause her to have great setbacks." I believe in generic meds wholeheartedly, I figured the new and improved drugs that claim they work better had to get their start somewhere. Right??? Carprofen was the answer for me and my girl. She has only had soft stools as a minimal side effect so far, I am keeping my fingers crossed as the medicine will undoubtedly will be increased as time prevails. She already was on an all organic dry food with us adding either meat, cheese and eggs to her meals and believe it or not, a small amount of vanilla ice cream as a bedtime snack for a high protein and great calcium diet. Now keep in mind not all Danes can handle this diet, this was done with a lot of research and great trial and error to find her balance. We have been to many specialist and tried many different medications to help Teagan live a comfortable life. I Thank you VetDepot for helping me make the right choice in arthritic medicine for my girl Teagan.