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Azodyl For Dogs & Cats

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Azodyl Kidney Health Supplements for Dogs & Cats

Rating: based on 12 reviews

What is Azodyl?

Azodyl is a nutritional supplement for dogs and cats that may support kidney function. When your pet is suffering from Chronic Kidney Disease (CKD), their kidneys no longer function as efficiently as they should. As a result of this progressive loss in renal function, harmful toxins like urea can build up in the blood, causing what is known as azotemia. Azotemia puts additional strain on the kidneys and can lead to further loss of kidney function.

Azodyl has a patented collection of natural bacteria (probiotics) that flush out uremic toxins in your pet's intestines. These probiotics may slow down toxin buildup and help prevent further kidney damage. Please note: Although Azodyl may remain unrefrigerated for a limited period of time, it is shipped expedited Monday through Thursday with insulated packaging and ice packs to minimize time spent unrefrigerated during shipping.


  • May enhance the kidneys' ability to eliminate toxins
  • Helps reduce azotemia in dogs and cats
  • A nutritional supplement with natural, beneficial probiotics
  • Manufacturer does not report any side effects associated with Azodyl
  • May be used along with other CKD therapies like special diets
  • Some animals may feel better in as little as 48 hours
  • May be suitable for use in animals with stage II to IV CKD

How it Works

Azodyl contains three strains of probiotics that eliminate uremic toxins that have diffused in your pet's intestines. Azodyl may prevent further kidney damage by providing natural enteric dialysis and slowing down toxin buildup in the blood.

Brand Name



Vétoquinol USA, Inc.


Azodyl is an over-the-counter (OTC) product that does not require a prescription. Available in quantities of 60 or 90 capsules.

Active Ingredients

Kibow Biotics® [E. thermophilus (KB 19), L. acidophilus (KB 27), B. longum (KB 31), Psyllium husk].

Common Misspellings

Azadol, Azodol, Azodyle, Azoydyl, Azidyl, Azadil, Azodil

Warranty and Manufacturer Information

Marketed by: Vetoquinol USA, Inc., 101 Lincoln Ave., Buena, NJ, 08310

Under License from: Kibow Biotech Inc., Newtown Square, PA, 19073 USA

NAC No.: 10050422

The above is provided for information purposes only and should not be used for the diagnosis or treatment of any condition. This information does not cover all possible variables, conditions, reactions, or risks relating to any topic, medication, or product and should not be considered complete. Certain product or medications may have risks and you should always consult your local veterinarian concerning the treatment of your pet. Any trademarks are the property of their respective owners.

How to Use Azodyl


Pet Weight Dosage
Dogs/Cats: Up to 5 lbs

Give 1 capsule daily

5–10 lbs

Give 2 capsules daily (1 in the AM and 1 in the PM)

Over 10 lbs Give 3 capsules daily (2 in the AM and 1 in the PM)

Side Effects

There are no reported side effects in the manufacturer's packaging materials. If you know of or suspect an overdose in your pet, seek immediate emergency veterinary care.


Azodyl may be used to support renal health in dogs and cats. Do not administer to other animals. Not for use in humans. Keep out of reach of children and animals, and do not permit children to handle Azodyl. Be sure to review the manufacturer's instructions and precautionary statements before use. Consult your veterinarian for instructions on safe and effective use in your pet.

This product must be refrigerated, and the capsules should be administered whole. Do not open, crush them, or mix their contents with your pet's food. If necessary, administer Azodyl with a piece of your pet's food, their favorite treat, or with the aid of products like Greenies Pill Pockets or Sentry Medi-Wraps. Allow your pet to have unrestricted access to fresh water while supplementing with Azodyl.


Store Azodyl in the refrigerator and keep out of reach of children and animals.

Azodyl Frequently Asked Questions

What is Azodyl and how does it work?

Azodyl is a nutritional supplement for dogs and cats that contains three strains of probiotics that may reduce azotemia, which is a medical condition characterized by an increased concentration of urea and other compounds in the blood that further impair kidney function.

How should Azodyl be used?

The manufacturer's recommended dose of Azodyl in cats and dogs weighing up to 5 lbs is 1 capsule daily. For animals weighing 5-10 lbs give 2 capsules daily (1 in the AM and 1 in the PM). For animals weighing greater than 10 lbs give 3 capsules daily (2 in the AM and 1 in the PM). If necessary, administer capsule with a piece of the animal's favorite food or treat. We recommend trying Pill Pockets if you have a finicky pet that doesn’t like to take pills.

What are the side effects?

According to the manufacturer's materials, there are no reported side effects.

What if a side effect occurs with my pet?

Stop administering Azodyl and contact your veterinarian.

How long does Azodyl take to work?

Depending on the overall health of your pet, the manufacturer says the reduction in BUN (blood urea nitrogen) and creatinine levels, two indicators that are used to measure renal health, may occur in as little as two weeks.

How long before or after food can Azodyl be taken?

Azodyl works best when it reaches your pet’s bowel. You want the medication to avoid spending a lot of time in your pet’s stomach and small intestine where there are acids that can be detrimental to the probiotics in Azodyl. By giving the medication not at feeding times, the better chance it has to quickly get to the colon.

Is Azodyl effective if the capsules are opened and given orally in water by syringe? Can I mix it with my pet’s food?

No. The manufacturer states that Azodyl has to be given whole. Do not open, crush, or give your pets the contents of Azodyl capsules via oral syringe. Doing so compromises the delivery system of the live probiotics. If necessary, try administering Azodyl with a piece of your pet’s favorite food or treats.

What happened to the 60 ct. bottles of Azodyl?

The 60 ct. bottles of Azodyl have been replaced by 90 ct. bottles that feature smaller capsules. Some pets, especially cats, had trouble swallowing the larger caspules. These new smaller capsules should alleviate that problem.

Does Azodyl need to be given on an empty stomach?

No. It does not need to be given on an empty stomach.

How long can Azodyl last without refrigeration?

The manufacturer has determined that Azodyl may remain unrefrigerated for a week or more, however we ship it in refrigerated packaging to insure viability. If you have concerns, please contact us at 1-800-710-9770.

How is Azodyl kept cold during shipping?

We ship Azodyl via UPS Overnight in insulated packaging with cold packs to make sure it stays properly refrigerated. However, The manufacturer has determined that Azodyl may remain unrefrigerated for a week or more. If you have concerns about the temperature of your product when you receive it, please contact us at 1-800-710-9770.

Does Azodyl have to be given to dogs with kidney disease?

Azodyl is a nutritional supplement designed to help pets suffering from Chronic Kidney Disease (CKD) by reducing the strain put on the kidneys. Consult your veterinarian to see if Azodyl can be used to augment any of the other CKD treatments your pet may be receiving.

What if my pet skips a day or two?

While there should be no harm if you get your pet back on the dosing regimen as soon as you can, contact your veterinarian to be sure.

Can Azodyl be given with simultaneous administration of antibiotics?

Pets with chronic kidney disease commonly contract urinary tract infections (UTIs), primarily due to the altered quantity and pH of their urine. Veterinarians usually prescribe various antibiotics to treat these sorts of infections. The manufacturer recommendeds that you space out the administration of the antibiotics and Azodyl by 6 hours. By then, the antibiotics will be fully absorbed and the half-life will be reduced sufficiently that any return to the gut will be negligible.

Will Azodyl help my pet’s kidney stones or urinary tract crystals?

While Azodyl is intended to support kidney function, it is not indicated for the treatment of kidney stones or urinary crystals. Please consult with your veterinarian before giving your pet Azodyl if they are already are taking urinary supplements.

Can my pet’s dosage be reduced?

You should follow the manufacturer's recommended dosage for your pet’s weight. The effectiveness of Azodyl may be reduced if you decrease the dosage. Please consult your veterinarian if you have specific questions about your pet's dosage.

Is there a liquid alternative to Azodyl?

Unfortunately, there are no similar products in liquid form.

What if one of my pets accidentally eats my other pet’s Azodyl capsule?

Because Azodyl is a nutritional supplement and may take up to two weeks before it takes effect, eating one capsule should not harm a pet not suffering from chronic kidney disease. Just make sure to get your affected pet back on the dosing regimen as soon as possible. Contact your veterinarian if you notice any potential side effects.

Does Azodyl cause an animal to lose balance?

Azodyl is a nutritional supplement, so it is unlikely that it would cause those symptoms. However, always consult with your veterinarian if you have any questions about your animal’s wellbeing.

Is Azodyl the same as Epakitin? What are their differences?

Azodyl and Epakitin are both kidney supplements, but they work in different ways. Azodyl may support renal function by reducing uremic toxins and easing the strain on your pet’s kidneys. It also has the potential to reduce BUN and creatinine levels. Epakitin is a kidney supplement that may reduce serum phosphorous levels.

Can my pet use Azodyl with Epakitin?

Yes. According to the manufacturer, Azodyl may be used with any chronic kidney disease treatment your pet is currently receiving, however you should always consult your veterinarian before giving your pet a new supplement or medication. Epakitin is primarily used for reducing serum phosphorous, and about 10-15% of patients with azotemia also have elevated serum phosphorous levels. When used together, Azodyl and Epakitin may help reduce both azotemia and phosphatemia. Please consult your veterinarian before giving your pet any new supplements or medications.

Can you use Rubenal and Azodyl together?

Yes. According to the manufacturer, Azodyl can be used with Rubenal. Rubenal is made from medicinal rhubarb and may help protect healthy kidney tissue and minimize the negative consequences of fibrosis. Azodyl uses probiotics to remove toxins from the blood that place extra strain on your pet’s kidneys. Both products may help pets with chronic kidney disease. However, consult your veterinarian before putting your pet on any supplement regimen.

Can I give my pet Azodyl and Aluminum Hydroxide?

Because different medications and supplements can interact differently with each other, you should speak to veterinarian about whether your pet should be taking Azodyl and Aluminum Hydroxide at the same time.

How long does Azodyl last in the refrigerator?

When stored in a refrigerator, Azodyl will last until the expiration date printed on the bottle.