Ketoconazole is a broad-spectrum, synthetic antifungal medication
belonging to the imidazole family of drugs. It treats fungal infections
by inhibiting ergosterol synthesis, which prevents fungal cells from
maintaining plasma membrane integrity. This causes the cell wall to
rupture.
Ketoconazole treats Cushing's disease by blocking the formation of
cortisol in the adrenal glands.
Warnings:
Keep this product out of reach of children and
animals. Do not use or store in or near open flame or heat.
Ketoconazole is intended for use in dogs. Do not
use in other animals unless specifically prescribed for that purpose
by your veterinarian. Do not use in humans. Although this medication
is sometimes used in cats, it may be toxic.
CAUTION: Numerous medications and supplements can interact
with Ketoconazole. Tell your veterinarian about any medications or supplements
your pet is taking before beginning therapy with this medication.
Do not give this medication to pregnant or nursing
pets.
Do not give Ketoconazole to pets taking astemizole,
triazolam, or cisapride. Doing so can cause serious and potentially
fatal side effects.
Rarely, this medication can cause severe liver
damage. Symptoms of liver damage may include nausea, vomiting, fatigue,
abdominal pain, reduced appetite, itching, dark urine, and yellow eyes.
Contact your veterinarian immediately if these symptoms develop in your
pet.
Symptoms of overdose include headache, nausea,
vomiting, dizziness, diarrhea, and abdominal pain. Seek immediate veterinary
attention for a known or suspected overdose.