Clomipramine

Separation Anxiety and Behavioral Disorder Medication

Clomipramine HCL is an antidepressant medication that controls separation anxiety and obsessive-compulsive behavior by altering neurotransmitter levels in the brain. This medication may also help minimize aggression and other negative behaviors in dogs. Clomipramine is most effective when used in conjunction with a behavior modification program.

Benefits of Clomipramine HCL:

• Improves daily behavior in dogs
• Does not affect your dog's personality
• Improves effectiveness of behavior modification programs
• Reduces aggressive behavior in dogs

Your dog's exact dose will depend on many factors, including individual response, severity of symptoms, and body weight. Follow the dosing instructions prescribed by your veterinarian. Do not attempt to calculate doses on your own.

Do not allow children to handle or administer this medication. Keep away from animals and children.

Directions:

1. Give Clomipramine with food.
2. Hand-feed 0.5 to 1.5 mg per pound of body weight to your dog once per day.
3. Treat cats with 0.5 mg per pound of body weight once per day.
4. Follow your veterinarian's exact dosing instructions, even if they differ from the usual dose.
5. Provide access to plenty of clean water while your dog is taking this medication.

Frequency of Use:

Keep giving this medication to your dog until your veterinarian tells you to stop. Symptoms may not improve immediately. It may take days or weeks of treatment before positive effects are observed.

Storage:

Store Clomipramine in its original container, tightly closed and at room temperature. Keep away from moisture, light, and heat. Do not store this medication in the bathroom or near the kitchen sink.

Store out of reach of children and pets.

It is a violation of Federal Law to use this product in a manner inconsistent with its labeling.

Clomipramine works by altering levels of serotonin, a neurotransmitter, in the brain. Balancing levels of serotonin can reduce anxiety, improve mood, and manage behavioral problems in some dogs.

Clomipramine (Anafranil)

Clomipramine is a tricyclic antidepressant.

Warnings:

Keep this product out of reach of children and animals. Do not use or store in or near open flame or heat.

Clomipramine HCL is intended for use in dogs only. It may also be used in cats. Do not give to other animals. Not for human use.

CAUTION: This medication may cause side effects in some animals. Possible side effects include dry mouth, reduced appetite, drowsiness, diarrhea, vomiting, and accelerated heart rate. Some dogs may exhibit increased aggressiveness while using Clomipramine.

Do not give Clomipramine to dogs that are allergic to it or to similar medications.

Use this medication cautiously and only under veterinarian supervision in animals with hyperthyroidism, liver disease, seizure disorders, urinary retention, and/or glaucoma. Not for use in pregnant or nursing animals. Do not use in breeding males.

Do not use Clomipramine with monoamine oxidase inhibitors (MAOIs). Wait a minimum of 2 weeks after stopping treatment with an MAOI before giving Clomipramine. Do not use with medications that depress the central nervous system, such as barbiturates.

Tell your veterinarian what medications and supplements your dog is taking before beginning treatment with Clomipramine. Consult your veterinarian before giving any new medications or supplements to your dog while being treated with this medication.

If an overdose is known or suspected, seek emergency veterinary care. Symptoms of an overdose include tachycardia, heart arrhythmia, and convulsions.

Clomipramine may alter blood glucose levels in pets.